What does Science Say about Omega-3 and Fatty Acids
and Specific Conditions


Minami Nutrition is about proof NOT promises. Our product range are produced as a result of our committment to research that examines the effect of Omega-3 fats on a variety of medical areas, including Dyslexia, Dyspraxia, Attention Deficit Hyperactivity Disorder (AD/HD) as well as Heart Disease and Wellness issues.

Clinical studies show that Omega-3 fatty acids are well tolerated by children and adults. The general consensus is that 1 g of EPA + DHA per day is sufficient to maintain optimum performance of the cardiovascular system in most people.* Ongoing scientific research is revealing more about the enormous potential for Omega-3 fatty acids to positively impact on a range of health outcomes.*


Heart and Cardiovascular Disease*:
Prevention = 1 g EPA + DHA/day
With high blood triglycerides = 2 to 4 g EPA + DHA/day

Attention Deficit Hyperactivity Disorder (AD/HD),

Dyslexia, Dyspraxia*:
0.5 to 1 g EPA/day


Depression*
1g (no DHA) day

Bipolar Disorder* 1- 2g (no DHA) day as supplementary treatment with standard therapy

Schizophrenia*:
2 g EPA/day as supplementary treatment with standard therapy


Mood Disorder (aggression)*:
1 to 2 g EPA/day


Pregnancy and Breast Feeding*:
220 to 800 mg EPA/day and 300 mg to 1 g DHA/day


Brain and Visual Development*:
20-40 mg DHA/2.2 lb. body weight/day


Preventive measures

- It is advisable not to take Omega-3 supplements if you are allergic to fish or gelatin It is advisable to tell your physician that you are taking Omega-3 supplements if you are about to have surgery or take anticoagulants


References

1. AHA: American Heart Association, 2002.
2. Marchioli R, Barzi F, Bomba E et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation 2002; 105(16):1897-903
3. Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother. 2002; 56(8):365-79.
4. ESC: European Society of Cardiology, 2003.
5. WHO/FAO: World Health Organisation, 2003.
6. ISSFAL: International Society for the Study of Fatty Acids and Lipids, 2004.
7. EFSA Journal 2009; 7(9):1263.
8. Origasa H, Yokoyama M, Matsuzaki M, Saito Y, Matsuzawa Y; JELIS Investigators. Clinical importance of adherence to treatment with eicosapentaenoic acid by patients with hypercholesterolemia. Circ J 2010; 74(3):510-7.
9. Ghiasvand R, Djalali M, Djazayery SA et al. Effects of eicosapentaenoic acid (PLUSEPAâ) and vitamin E on the plasma levels of antioxidant vitamins and inflammatory markers, and on erythrocyte antioxidant enzyme activities, in male basketball players. Acta Medica Iranica 2009; 47(4): 269-274.
10. Bloomer RJ, Larson DE, Fisher-Wellman KH, Galpin AJ, Schilling BK. Effect of eicosapentaenoic and docosahexaenoic acid on resting and exercise-induced inflammatory and oxidative stress biomarkers: a randomized, placebo controlled, cross-over study. Lipids Health Dis 2009; 8:36.

11. Peet M, Horrobin DF. A dose-ranging study of the effects of ethyl-eicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs. Arch Gen Psychiatry 2002; 59(10):913-9.

 

12. Jazayeri S, Tehrani-Doost M, Keshavarz SA et al. Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid (PLUSEPAâ) and fluoxetine, separately and in combination, in major depressive disorder. Aust N Z J Psychiatry 2008; 42(3):192-8.
13. Jazayeri S, Keshavarz SA, Tehrani-Doost M, Djalali M, Hosseini M, Amini H, Chamari M, Djazayery A. Effects of eicosapentaenoic acid (PLUSEPAâ) and fluoxetine on plasma cortisol, serum interleukin-1beta and interleukin-6 concentrations in patients with major depressive disorder. Psychiatry Res 2010; 178(1):112-5.
14. Rogers PJ, Appleton KM, Kessler D et al. No effect of n-3 long-chain polyunsaturated fatty acid (EPA and DHA) supplementation on depressed mood and cognitive function: a randomised controlled trial. Br J Nutr 2008; 99(2):421-31.
15. Montgomery P, Richardson AJ. Omega-3 fatty acids for bipolar disorder. Cochrane Database Syst Rev 2008; (2):CD005169.
16. Gustafsson PA, Birberg-Thornberg U, Duchén K et al. EPA (PLUSEPAâ) supplementation improves teacher-rated behaviour and oppositional symptoms in children with ADHD. Acta Paediatr 2010; 99(10):1540-9.
17. Antypa N, Van der Does AJ, Smelt AH, Rogers RD. Omega-3 fatty acids (fish-oil) and depression-related cognition in healthy volunteers. J Psychopharmacol 2009; 23(7):831-40.
18. Simopoulos AP, Leaf A, Salem N Jr. Workshop statement on the essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids 2000; 63(3):119-21.
19. Facchinetti F, Fazzio M, Venturini P. Polyunsaturated fatty acids and risk of preterm delivery. Eur Rev Med Pharmacol Sci 2005; 9(1):41-8.
20. Koletzko B, Cetin I, Brenna JT et al. International Society for the Study of Fatty Acids and Lipids. Dietary fat intakes for pregnant and lactating women. Br J Nutr 2007; 98(5):873-7.

 


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What does Science Say
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Message of the Founder
Jo Wyckmans